Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep172 | Reproduction, endocrine disruptors and signalling | ECE2015

Reduction of growth and lesser utilisation of energy reserves in heroin addicted boys during pubertal development

Saqlain Muhammad , Raja Ghazala Kaukab , Akram Maleeha , Minallah Samar , Ahmad Afzaal , Qayyum Mazhar , Rizvi Shakeel Raza

The secretion of leptin, an indicator of energy reserves, declines as energy stores are consumed in growth and development at puberty. The pubertal growth and development are often altered under different kinds of stresses. Usually, stress stimulates the release of cortisol, which is a labelled marker of stress. Early teens are inclined to drug abuse that may put their bodies under stress and may induce excessive secretion of cortisol. Since, sustained high levels of cortisol ...

ea0056p668 | Neuroendocrinology | ECE2018

Cigarette smoking and neuroreceptors genetic variations: a handshake between genetic and environmental factors leading to nicotine addiction

Zafar Muhammad Mobeen , Ahmad Imtiaz , Raja Muhammad Saqlain , Kiani Shagufta , Ahmed Muhammad Sheeraz , Raza Shakeel , Gulfraz Muhammad , Kaukab Ghazala

Cigarette smoking is the major cause of disease related deaths in the world. Cigarette smoke contains many harmful chemicals, among them nicotine is the most potent one. The root cause of smoking hazards is nicotine addiction or dependence (ND). Environmental as well as genetic factors are reported to influence smoking which leads to nicotine addiction in all age groups especially. Neurexin1 is a cell adhesion protein important for synapse formation and CHRNB4 is chol...